Vitamin D2

CAS No. 50-14-6

Vitamin D2( Calciferol | Ergocalciferol | Fortodyl | Infron | Mulsiferol | NSC 62792 | Radiostol | Uvesterol D )

Catalog No. M14687 CAS No. 50-14-6

Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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500MG 38 In Stock
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Biological Information

  • Product Name
    Vitamin D2
  • Note
    Research use only, not for human use.
  • Brief Description
    Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells.
  • Description
    Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.(In Vivo):At sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food.Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies.
  • In Vitro
    ——
  • In Vivo
    At sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food.Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies. Animal Model:83 chickens (White Leghorn), weighing 318 ± 9 g.Dosage:250,000 IU/kg Administration:S.C. once daily.Result:Induced a long-lasting hypercalcemia in rat and mice and suppresses the expression of PTH mRNA in the rat.
  • Synonyms
    Calciferol | Ergocalciferol | Fortodyl | Infron | Mulsiferol | NSC 62792 | Radiostol | Uvesterol D
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA polymerase| VD3
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    50-14-6
  • Formula Weight
    396.65
  • Molecular Formula
    C28H44O
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 80 mg/mL (201.68 mM); DMSO: 20 mg/mL (50.42 mM)
  • SMILES
    O[C@@H]1C/C(C(CC1)=C)=C/C=C2[C@]3([H])CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]3(C)CCC/2
  • Chemical Name
    (S,Z)-3-(2-((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexan-1-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mizushina Y, et al. J Pharmacol Sci. 2003 Jul;92(3):283-90.
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